Four meta-analysis of clinical trials of garlic on humans show that it has cholesterol lowering effects of between 8-15% [1,2,3,4].
Studies have also shown that garlic has anti-clotting properties for heart protection – by its fibrinolytic activity (clot breaking) [5,6] and inhibition of platelet aggregation (clot forming) [7,8].
1. Silagy, C & Neil, A. Garlic as a lipid lowering agent – a meta-analysis. J R Coll Physician Lond 1994, 28:39-45
2. Warshafsky, S et al. Effect of garlic on total serum cholesterol – A meta-analysis. Ann Intern Med 1993, 119:599-605
3. Neil, HA et al. Garlic powder in the treatment of moderate hyperlipidemia: a controlled trial and meta-analysis. J R Coll Physicians Lond 1996, 30:329-334
4. Stevinson, C et al. Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials. Ann Intern Med 2000, 133: 420-429
5. Bordia, AK et al. Effect of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery disease. Atherosclerosis 1977, 28:155
6. Chutani, SK et al. The effect of fried versus raw garlic on fibrinolytic activity in man. Atherosclerosis 1988, 38:417-421
7. Bordia, A. Effect of garlic on human platelet aggregation in vitro. Atherosclerosis 1978, 30:355-360
8. Kiesewetter, H et al. Effect of garlic on thrombocyte aggregation, microcirculation, and other risk factors. Int J Clin Pharmacol Ther Toxicol 1991, 29:151-155
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